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Saturday, May 18, 2024

Can Red Cabbage Juice Help Alleviate Inflammatory Bowel Disease? Researchers at the University of Missouri Think So

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Mun Y. Choi, PhD, President | University of Missouri

Mun Y. Choi, PhD, President | University of Missouri

A team of researchers at the University of Missouri, led by Satyanarayana Rachagani, has been investigating the potential benefits of red cabbage juice in alleviating inflammation-associated digestive health conditions such as inflammatory bowel disease (IBD). Rachagani explains that red cabbage juice alters the composition of gut microbiota, promoting the growth of good bacteria and increasing the production of beneficial metabolites that help in reducing inflammation.

Rachagani stated, "Red cabbage juice alters the composition of gut microbiota by increasing the abundance of good bacteria, resulting in increased production of short chain fatty acids and other bacteria derived metabolites ameliorating inflammation."

Nagabhishek Sirpu Natesh, a post-doctoral fellow on the team, highlighted the positive effects of red cabbage juice treatment on mice, stating that it increased good gut bacteria and triggered an anti-inflammatory response in the colons of the mice. The juice also boosted regulatory T cells, which play a role in promoting an anti-inflammatory immune balance.

The researchers found that red cabbage juice could potentially offer a new approach to treating IBD, as opposed to the current primary pharmacological approach using monoclonal antibodies. Rachagani emphasized, "Its ability to modulate gut microbiota, activate anti-inflammatory pathways and enhance immune regulation underscores its potential as a valuable therapeutic agent for IBD and related inflammatory disorders."

The study, supported by grants from the National Science Foundation, National Institutes of Health, and Nebraska Research Initiative, was recently published in a scientific journal. The team included researchers such as Christian Lorson and Jussuf Kaifi from the University of Missouri.

The findings from this research offer hope to the millions of Americans suffering from IBD, suggesting that red cabbage juice could potentially be a natural and effective way to alleviate symptoms and improve gut health.

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