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Show-Me State Times

Friday, November 7, 2025

CEO of the Pacific Research Institute on misuse of 340B funds: ‘340B was meant to help low-income patients’ as scrutiny grows in Missouri

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Sally Pipes | Provided photo

Sally Pipes | Provided photo

Sally Pipes, President and CEO of the Pacific Research Institute, said the 340B program has strayed from its original mission, allowing wealthy hospitals to profit while offering little charity care, a concern drawing attention in Missouri. The announcement was made on X.

The federal 340B Drug Pricing Program, created in 1992, requires drug manufacturers to offer steep discounts to eligible hospitals and clinics that serve low-income or uninsured patients. According to the Association of American Medical Colleges (AAMC), these savings are intended to help safety-net providers stretch resources and expand access to essential medications, though oversight gaps have raised concerns about uneven benefits.

A New York Times investigation in 2022 found that many non-profit hospitals across the U.S., including those benefiting from the 340B program, billed poor patients who were eligible for free or discounted care and devoted minimal spending to charity care. Some large systems spent less than 2% of their expenses on helping low-income patients, despite receiving tax breaks and federal program benefits.

PhRMA reported that 42 hospitals in Missouri participate in the 340B program, maintaining more than 1,400 contracts with pharmacies nationwide. Only 22% of those pharmacies are in medically underserved areas, while 79% of hospitals provide charity care below the national norm—raising doubts about how effectively the program serves its target communities.

Sally C. Pipes has served as President and CEO of the Pacific Research Institute since 1991, where she leads research and advocacy on healthcare, education, and economic policy. A prominent voice for free-market healthcare reform, she promotes patient-centered solutions that expand access and affordability. Pipes is also a regular columnist for Forbes and National Review, writing extensively on policy innovation and government reform.